Pruritus is a medical term that means itching. It refers to a feeling or sensation on your skin that you want to scratch. Pruritus can be painful or irritating and could be localized to one area of your body or spread throughout several areas. Itch has been classified into four different clinical categories. These include neurogenic, psychogenic, neuropathic, and pruritoceptive developed based on anatomical, pathophysiological, and psychological factors.